How much Difluoroethane is toxic?

How much Difluoroethane is toxic?

HUMAN EXPOSURE AND TOXICITY: Several volunteers were exposed to 500,000 ppm of HFC 152a for several min. Analgesia and an impending loss of consciousness were reported. Rapid evaporation of the liquid may cause frostbite. The substance may cause effects on the cardiovascular system , resulting in cardiac disorders.

What refrigerant is Difluoroethane?

R-152a
1,1-Difluoroethane, or DFE, is an organofluorine compound with the chemical formula C2H4F2. This colorless gas is used as a refrigerant, where it is often listed as R-152a (refrigerant-152a) or HFC-152a (hydrofluorocarbon-152a). It is also used as a propellant for aerosol sprays and in gas duster products.

How long does Difluoroethane stay in your system?

In cases of traffic accidents, 1,1-difluoroethane was able to be detected in blood up to three hours after the time of abuse (10).

What is Difluoroethane intoxication?

Abstract. 1,1-Difluoroethane (DFE) is a halogenated hydrocarbon used as a propellant in products designed for dusting electronic equipment and air brush painting. When abused, inhaled DFE produces intoxication and loss of muscular coordination.

How long does difluoroethane stay in your system?

What is intoxication by difluoroethane?

How long does Difluoroethane stay in your blood?

Is Difluoroethane flammable?

ICSC 1729 – 1,1-DIFLUOROETHANE. Extremely flammable. Gives off irritating or toxic fumes (or gases) in a fire. Gas/air mixtures are explosive.

What is the main ingredient in dust off?

Dust-Off, a popular brand name of canned air, is a gaseous refrigerant-based propellant cleaner used to remove dust and dirt from computers and electronics. The main ingredient in Dust-Off is difluoroethane.

What is Difluoromethane used for?

Difluoromethane is a molecule used as refrigerant that has prominent heat transfer and pressure drop performance, both in condensation and vaporization. It has a 100-year global warming potential (GWP) of 675 times that of carbon dioxide, and an atmospheric lifetime of nearly 5 years.

How dangerous is 1 1 difluoroethane?

If mass peaks corresponding to 1,1-difluoroethane are observed immediately after spraying a suspect leak point, leaks may be identified. Difluoroethane is an intoxicant and precipitates fatal cardiac arrhythmia. Several reports of fatal car crashes have been linked to drivers huffing 1,1-difluoroethane.

How much difluoroethane does it take to kill rats?

When the rats were exposed by inhalation to 1,2-difluoroethane (624-72-6), 1-chloro-2-fluoroethane (762505), 1-bromo-2-fluoroethane (762492), or 1-chloro-1,2-difluoroethane (338647) for 4 hours, the lethal concentrations for each compound were less than 100 parts per million (ppm).

Do fluorinated ethanes cause inhalation toxicity?

Abstract: The inhalation toxicity of a series of fluorinated ethanes which are metabolized to fluoroacetate (144490) were studied in the male CD-rat.

Is fluorocitrate elevated in rats exposed to difluoroethane?

Rats exposed to 1,2-difluoroethane showed fluorocitrate in the kidneys. Rats exposed to 1,2-difluoroethane showed a concentration related elevation of serum and heart citrate up to 1000ppm of the compound.