Is 3000 mg of Depakote too much?

Is 3000 mg of Depakote too much?

Most patients take a total of 750 to 3,000 mg each day. Taking more than 4,000 mg per day is seldom recommended. Patients who have been taking regular Depakote or Depakene will need to take 8% to 20% more Depakote ER to achieve the same effect.

Is 2500 mg of Depakote too much?

Depakote tablets are administered orally. The recommended starting dose is 250 mg twice daily. Some patients may benefit from doses up to 1,000 mg/day. In the clinical trials, there was no evidence that higher doses led to greater efficacy.

Is 1500 mg of Depakote too much?

Is 1000 mg of Depakote a lot?

The recommended starting dose of Depakote for the prevention of migraine is 250 mg twice daily. The dose may be increased until migraine control is achieved. The maximum recommended dose is 1000 mg/day as needed.

How much Depakote is lethal?

400 — 1000 mg/kg: severe toxicity, i.e. Coma.

Why is Depakote hazardous?

Depakote side effects include damage to the liver and pancreas. In 2006, the FDA required that the drug’s label feature a black-box warning indicating an increased risk of pancreatitis and liver failure. Evidence suggests that hepatotoxicity most typically occurs within the patient’s first six months taking Depakote.

Can Depakote overdose cause death?

Valproic acid (sodium valproate) in overdose results in CNS depression and large overdoses can result in multi-system organ failure and death.

Can you OD from Depakote?

An overdose of Depakote could be fatal, so seek immediate help or call the Poison Help Line at 1-800-222-1222 if you overdose. Overdose symptoms can include irregular heartbeat, sleepiness, and loss of consciousness resulting in a coma.

What happens if you OD on Depakote?

Is Depakote fatal?

Can I take 1500 mg of Depakote?

Maintenance dosage in usually in the range of 1000-1500 mg. daily, sometimes higher. The target blood level is 50-100 micrograms/milliliter of blood, though some people’s symptoms are best controlled at slightly lower or higher levels.

Is 2000 mg of Depakote a lot?

The mean daily dose usually ranges between 1000 – 2000 mg valproate. Patients receiving daily doses higher than 45 mg/kg/day body weight should be carefully monitored. Continuation of treatment of manic episodes in bipolar disorder should be adapted individually using the lowest effective dose.