Why should film coated tablets not be crushed?

Why should film coated tablets not be crushed?

Crushing enteric coated tablets may result in the drug being released too early, destroyed by stomach acid, or irritating the stomach lining. In general, manipulation of enteric coated and extended-release formulations is not, therefore, recommended.

Do film coated tablets dissolve?

14.4. An enteric coating resists dissolution under acidic conditions, but is freely soluble at the more basic conditions of the intestinal tract. Enteric coating may be used to protect acid-labile drugs or to avoid gastric distress induced by high concentrations of some drugs, such as aspirin.

Can you cut film coated tablets in half?

Splitting pills can be dangerous Not all pills can be cut in half safely, especially coated tablets and time-release capsules. Avoid splitting any medication labeled as an “enteric-coated tablet,” including some over-the-counter pain relievers and back pain medications.

Can you half film coated tablets?

What is the purpose of film coated tablets?

Film coating is a common step in tablet manufacture that can be used to improve product appearance, organoleptic properties, or to facilitate swallowing. Functional film coats can also be used as a part of the product’s stabilisation strategy and to modify or delay drug release.

Are all tablets film coated?

Tablets can either be ‘sugar coated’, ‘film coated’, ‘enteric coated’ or coated to modify how the drug is released into the body (modified release). Each of these coatings are there for different reasons and it is important to understand these reasons before deciding whether it is safe or appropriate to crush tablets.

Why we use film coated tablets?

Why can you not crush diltiazem?

The capsules are made so that there is slow release of the drug. These capsules should be swallowed whole. However, the beads may be removed from inside capsules to separate smaller daily doses. Please ask your pharmacist about doing this.

Why can diltiazem be crushed?

Swallow the capsules whole. Do not crush or chew the capsules. Doing so can release all of the drug at once and may increase your risk of side effects.