What is Octadecylsilyl silica gel column?

What is Octadecylsilyl silica gel column?

Products/Services for Octadecylsilyl Silica Gel HPLC Columns. HPLC Columns – (163 companies) High performance liquid chromatography (HPLC) is a separation technique that uses liquid mobile phase to separate the components of a mixture.

What is base deactivated silica?

Base deactivated silica relates to “low silanol activity”. Silanol activity is responsible for peak tailing of basic molecules at mid-pH and it is caused by the presence of metal contamination embedded in the silica substrate (introduced from the starting mateirals and the manufacturing process).

What is L7 column?

L7 USP columns are described as octyl silane (C8), chemically linked to porous silica particles, 1.5 to 10 µm in diameter. Our high-quality L7 USP columns include: LiChrosorb® RP-8 (5 µm).

What is C8 column?

C8 column is a type of column used in the reverse-phase chromatography. Generally, the reverse-phase chromatography uses a hydrophobic stationary phase. However, the solid support stationary phase or the column contains modified silica. Here, silica is a hydrophilic stationary phase.

What is the difference between C18 and C8 columns?

C18 has 18 carbon atoms while C8 has only 8 carbon atoms. C18 has a longer carbon chain, but C8 has a shorter one. C18 has higher retention while C8 has shorter retention. C18 has higher hydrophobicity, but C8 has a lower hydrophobicity.

What is difference between ODS and BDS column?

ODS and BDS are two columns used for reverse-phase chromatography. The key difference between ODS and BDS column is that ODS column contains free –OH functional groups, whereas BDS column contains deactivated –OH groups.

What is hypersil BDS column?

Hypersil BDS (Base Deactivated Silica) phases are widely referenced in legacy methods. They are robust, general purpose columns for use in a wide range of applications in QA/QC laboratories. Hypersil BDS columns exhibit reduced silanol activity compared to Hypersil Classical phases.

What is phenyl column?

Phenyl columns are first reversed-phase columns, and give retention just as other reversed-phase columns. Next they give specific retention increments for analytes that interact via pi-pi interactions, or a lack of increment for analytes that do not have such specific interactions.

What is the difference C8 and C18 HPLC column?

Which is better C8 or C18 column?

C18 is considered better for separating compounds such as long-chain fatty acids as compared to relatively small organic compounds. C18 has a longer carbon chain, but C8 has a shorter one. C18 has higher retention while C8 has shorter retention. C18 has higher hydrophobicity, but C8 has a lower hydrophobicity.

What is BDS column in HPLC?

BDS column is a type of reverse-phase HPLC column which has blocked –OH groups. This means the hydroxyl groups in this column are deactivated/not free. It is also named as BDS C18 column, and this column is packed with octadecasilane chains. The term BDS stands for Base Deactivated Silica.

Is C18 column polar or nonpolar?

A C18 column is an example of a “reverse phase” column. Reverse phase columns are often used with more polar solvents such as water, methanol or acetonitrile. The stationary phase is a nonpolar hydrocarbon, whereas the mobile phase is a polar liquid.

What is the size of L1 octadecyl silane?

USP “L” Column Listing L1 Octadecyl silane (ODS or C 18) chemically bonded to porous silica or ceramic particles – 1.5 to 10 µm in diameter. See new subclassification table on previous page. Brand Particle Size Type Page AccQ•Tag Ultra 1.7 Spherical 240 ACQUITY UPLC CSH C 18 1.7 Spherical 91 ACQUITY UPLC BEH C 18 1.7 Spherical 93

How does silica gel affect polymerization?

Silica Products for a Variety of Applications of the silica gel have a significant effect on both the polymerization process and properties of the finished polymer. The pore structure, spherical shape and particle distribution of SUNPSERA TM for catalyst support are precisely defined.

What is MS Gel for sec-2020?

M.S GEL is a liquid chromatography column packing agent available in an average particle size range of 1.6 to 300 um with narrow particle size distribution. Additionally, the average pore diameter control range is 80 to 1000 A and the pore size… (read more) M.S. GEL ™ Fine Silica for Chromatography MS GEL for SEC-2020.

What is rereversed-phase C18 columns?

Reversed-Phase C18 Columns （ ODS ） Low molecular weight compounds High molecular weight compounds Alkaline mobile phase General organic compounds Basic compounds Coordination compounds Sugars and glycosides