What does it mean when hepatitis B core antibody is negative?

What does it mean when hepatitis B core antibody is negative?

Normal results are negative or nonreactive, meaning that no hepatitis B core IgM antibodies were found. If your test is positive or reactive, it may mean you are actively infected with HBV. In most cases, this means that you will recover within 6 months.

What does it mean when you are HBsAg positive and HBeAg negative?

In HBV carriers and patients with chronic hepatitis B, positive HBeAg results usually indicate presence of active HBV replication and high infectivity. A negative HBeAg result indicates very minimal or no HBV replication. Positive anti-HBe results usually indicate inactivity of the virus and low infectivity.

What is the difference between Hep B surface antigen and antibody?

HBsAg: Hepatitis B surface antigen is a marker of current infection. Its presence indicates either acute or chronic HBV infection. Anti-HBs: Antibody to hepatitis B surface antigen is a marker of immunity.

What is core antibody in hepatitis?

The hepatitis B core antibody (HBcAb) is produced by your immune system after infection by the hepatitis B virus, and it can persist for life. It is a sign that you either have an new, active (acute) hepatitis B infection or that you acquired hepatitis B in the past.

What is Hep B core antibody positive?

anti-HBc or HBcAb (Hepatitis B core antibody) – A “positive” or “reactive” anti-HBc (or HBcAb) test result indicates a past or current hepatitis B infection. The core antibody does not provide any protection against the hepatitis B virus (unlike the surface antibody described above).

What does a positive Hep B core Ab total mean?

Hepatitis B Core Antibody (HBcAb or Anti-HBc) – This antibody does not provide any protection or immunity against the hepatitis B virus. A positive or “reactive” test indicates that a person may have been infected with the hepatitis B virus at some point in time.

Is HBeAg-negative good or bad?

HBeAg‐negative CHB is a potentially severe disease that rapidly progress to cirrhosis and related complications. Although treatment is available, sustained virological and biochemical response is poor after the recommended duration of treatment.

Can HBsAg turn negative?

Patients who become HBsAg negative and develop antibody to HBsAg (anti-HBs) are diagnosed as having resolved hepatitis B [3,4]. This is an uncommon phenomenon in chronic HBV infection.

What does it mean to have a positive hepatitis B core antibody?

What does a positive hepatitis B core IgM mean?

IgM antibody to hepatitis B core antigen (IgM anti-HBc): Positivity indicates recent infection with hepatitis B virus (<6 mos). Its presence indicates acute infection. Tests.

Does hepatitis B core antibody positive mean?

What does core antibody mean?

The test for hepatitis B core antibody detects the presence of the core protein of the virus. A positive result means the person has been infected with HBV, but it does not specify whether the person has cleared the virus, still has the infection, or is immune to reinfection.